Is there any way to have Chrome default to an alternate profile when accessing certain sites, or disable all extensions on certain sites? Ideally I'd like to u

Is there any way to have Chrome default to an alternate profile when accessing certain sites, or disable all extensions on certain sites? Ideally I'd like to use one profile with no extensions for financial sites, and a separate profile for e-commerce sites, but it requires that I remember to switch to that profile prior to logging-in. Maybe I could block the sites in the profile I use for development to force me to isolate those activities in a "clean" profile.