Take a look at their "Convenience API" (http://toyplot.readthedocs.io/en/stable/convenience-api.html http://toyplot.readthedocs.io/en/stable/convenience-api.htm

Take a look at their "Convenience API" (http://toyplot.readthedocs.io/en/stable/convenience-api.html http://toyplot.readthedocs.io/en/stable/convenience-api.html) that does indeed make simple two-axis plots a one-liner. toyplot.plot(x, y) seems pretty hard to beat!