3 ms·
Hi, that's an interesting study. Cows are known to have antibodies with unique conformations, probably since their metabolism involves bacterias much more than
by Protostome 9y ago
Hi, that's an interesting study.
Cows are known to have antibodies with unique conformations, probably since their metabolism involves bacterias much more than other mammals, such as ourselves.
Antibodies are molecules that are generated by B-Cells and upon exposure to an invader, some antibodies go through rapid evolution.
The unique conformation of a cow antibody allows it to bind to deep pockets and places that human antibodies may have some difficulties reaching.
With that said, while this research is interesting, the implications for human therapeutics are mostly negligible.
Cow's antibody cannot be transferred safely to humans since they will elicit an immune reaction and will probably be considered a foreign invader.
Also, there's no shortage in human origin broadly neutralizing antibodies for HIV. Those are still not considered the best line of defence.