I'm not sure how accurate the little graph google gives you when you search "baltimore population" is, but it looks like the population is falling. Less people

I'm not sure how accurate the little graph google gives you when you search "baltimore population" is, but it looks like the population is falling. Less people means less commerce which means less demand for buildings. Perhaps those rundown empty buildings have not enough value for someone to invest in fixing them up (and therefor, have no incentive to employ people to do so).