I'm more interested in sustained weight loss over the rest of person's life. Best I can tell, that is predicated on reducing insulin resistance while not restri

I'm more interested in sustained weight loss over the rest of person's life. Best I can tell, that is predicated on reducing insulin resistance while not restricting calories too much. People don't stick with reduced calorie diets, and human body can (and does) reduce its metabolic rate to compensate for reduced calorie intake, thus defeating it.