3 ms·
This isn't all that, because the genetics of longevity will have next to no impact on the future of your own personal longevity. http://www.fightaging.org/arch
by reasonattlm 16y ago
This isn't all that, because the genetics of longevity will have next to no impact on the future of your own personal longevity.
http://www.fightaging.org/archives/2010/06/there-will-be-ten-thousand-subtle-gene-variants-of-human-longevity.php http://www.fightaging.org/archives/2010/06/there-will-be-ten...
http://www.fightaging.org/archives/2010/06/another-illustration-as-to-why-there-will-be-many-many-genetic-contributions-to-longevity.php http://www.fightaging.org/archives/2010/06/another-illustrat...
We should expect to see subtle associations with human longevity in genes associated with processes known to be important in long-term health - such as the inflammatory response, or indeed anything else associated with the operation of the immune system. But what can be done with this information? As things stand, probably little of consequence. All new knowledge in the biology of human aging will prove useful eventually, but in the near term it seems very unlikely that as much benefit can be derived from such exploration and analysis as from, say, effort put into developing repair technologies for the known forms of age-related damage.
We humans have a lot of genes, which means there is a very, very large number of potential interactions between gene variants - even within a subset of genes associated with a specific biological system. Discovery and understanding in the face of this complexity represents an enormous amount of work, which is one of the reasons that researchers who favor the metabolic manipulation approach to aging believe that we are a long way from any significant slowing of aging or extension of the healthy human life span.