I would say, eschew any fancy front end framework. Build an HTML form. They're tab-able by default. You can even tab to a button and hit enter to press it from

I would say, eschew any fancy front end framework. Build an HTML form. They're tab-able by default. You can even tab to a button and hit enter to press it from the keyboard. Separate out the UI and business logic, and you can probably port most of it to a backend MVC (where view means a template, meaning HTML) framework in VisualBasic. Once it is cleaned up, you can do a feature-by-feature rewrite in your backend language of choice (I'd likely recommend Django if you can go Python, but SparkJava might be more prudent for the kind of big freaking Enterprise that chooses to do stuff in VB). Edit: after seeing https://news.ycombinator.com/item?id=14787139 https://news.ycombinator.com/item?id=14787139 I agree that you'll probably need handsontable or something like it. Simplicity is your friend; overengineering is unfortunately a common tendency among developers of all stripes, although the web kind especially.