> What is the selective pressure /for/ cancer-predisposing genes? Evolution does not and never has selected /for/ things. It is a process of elimination. What

> What is the selective pressure /for/ cancer-predisposing genes? Evolution does not and never has selected /for/ things. It is a process of elimination. What this means is that, since the advent of chemotherapy, we have eliminated selection /against/ certain types of cancer. > the majority of them emerge well after the onset of reproductive ability Correct, we have never had an impact on that and likely won't for a very long time (we don't know enough about our genome to do so). As-per this study, we have been curing cancer in children (as we absolutely should) with very little knowledge as to how/why they developed cancer so young. Will their children also be at risk for leukemia? What about their millions of descendants? We don't know. If treatments like this work out then we might not have to care.