Only if it would apply to all alien civilizations. The thing about Fermi's paradox is that the Universe is old and the local galaxy is big, so any explanation

Only if it would apply to all alien civilizations. The thing about Fermi's paradox is that the Universe is old and the local galaxy is big, so any explanation for the apparent absence of ETI has to cover all ETIs. It just takes one species in galactic history to reach the point of launching a self-replicating interstellar probe to produce a galaxy permanently aswarm with them. Heck, we're not that far away from being able to do so ourselves. And any explanation of the form "the ETIs wouldn't do that because reasons" just fails, because it just takes one event, over a very long time and large number of systems.