3 ms·
To be fair, the predictive power of many different polygenic risk models is very low. (Source: doing a PhD in Genetics atm.) So this does not really surprise me
by deugtniet 9y ago
To be fair, the predictive power of many different polygenic risk models is very low. (Source: doing a PhD in Genetics atm.) So this does not really surprise me. Usually about 50% of variance can be explained by genetics, and 50% by environment. Meaning that if you have a good enviromental predictor, such as a zip code, you may be able to predict a trait better, than with genetics, which contain a lot of cryptic relationships that a predictor may not integrate. Its totally fair to be critical of the merit of genetic predictions. Usually they are super bad.