It's not intuitively obvious that acetaminophen has a startlingly small therapeutic window, especially when combined with alcohol. It's not intuitively obvious

It's not intuitively obvious that acetaminophen has a startlingly small therapeutic window, especially when combined with alcohol. It's not intuitively obvious that alcohol may reduce all-cause mortality in a hormesis-like fashion, with low chronic consumption reducing risk but high chronic consumption increasing it. Pharmacology == intuition goes out the window.