3 ms·

I'm not sure. Anything that has psychoactive effects seems like it would be in a league of its own (caffeine, alcohol, cocaine, LSD, etc.).

• kortex 9y ago
  It's not intuitively obvious that acetaminophen has a startlingly small therapeutic window, especially when combined with alcohol. It's not intuitively obvious that alcohol may reduce all-cause mortality in a hormesis-like fashion, with low chronic consumption reducing risk but high chronic consumption increasing it. Pharmacology == intuition goes out the window.
  • dvt 9y ago
    That's kind of my point, acetaminophen is a psychoactive drug.