3 ms·

There's a pretty intuitive difference between moonshine and a banana.

• lotsofpulp 9y ago
  But not between a joint and a twinkie, or 20oz soda, or a deep fried <anything>.
  • dvt 9y ago
    I'm not sure. Anything that has psychoactive effects seems like it would be in a league of its own (caffeine, alcohol, cocaine, LSD, etc.).
    • kortex 9y ago
      It's not intuitively obvious that acetaminophen has a startlingly small therapeutic window, especially when combined with alcohol. It's not intuitively obvious that alcohol may reduce all-cause mortality in a hormesis-like fashion, with low chronic consumption reducing risk but high chronic consumption increasing it. Pharmacology == intuition goes out the window.
      • dvt 9y ago
        That's kind of my point, acetaminophen is a psychoactive drug.