I've been a web developers for 5 years like the author, and, I as well, went through the jQuery, Knockout, Backbone, React, Vue road. On my daily job I use Node

I've been a web developers for 5 years like the author, and, I as well, went through the jQuery, Knockout, Backbone, React, Vue road. On my daily job I use Node & React/Redux, on personal projects, I prototype in Python using bottle and vanilla JavaScript with axios[1]. Before, I wanted to use the latest stack, maybe looking for approval from the "community", something like: "Hey, I'm building a X app with Express, React, React Router, Redux, Immutable..." But by the time I had the basic setup, my motivation was gone (at that time there was no react-starter-app[2]). So I'd say you should start with whatever you are most comfortable, doesn't matter if it's React or jQuery. The goal, IMO, is to start building stuff. Now, I just don't care what's the latest JS framework, I don't dislike them, all the opposite, I get excited about them[3], but I focus on what's my best weapon for the job. - [1] https://github.com/mzabriskie/axios https://github.com/mzabriskie/axios - [2] https://github.com/facebookincubator/create-react-app https://github.com/facebookincubator/create-react-app - [3] https://github.com/KingPixil/moon https://github.com/KingPixil/moon