I'm sure it would work, but you wouldn't get a lot of the benefits like a global distributed cache (API Gateway uses Cloudfront as it's cache), and you're obvio

I'm sure it would work, but you wouldn't get a lot of the benefits like a global distributed cache (API Gateway uses Cloudfront as it's cache), and you're obviously dependant on support from a very low cost supplier in the event of a problem with the hardware. Would it be worth introducing that support dependency for ~$200 a month? Maybe, I guess it depends on what you're making from the service.