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So why does the AHA still say that saturated fat raises LDL, and cites multiple trials? This goes beyond the media and Ancel Keys. Are these studies not able to

So why does the AHA still say that saturated fat raises LDL, and cites multiple trials? This goes beyond the media and Ancel Keys. Are these studies not able to control for confounding factors like replacing the sat. fat with sugars and refined carbs? For what it's worth I don't think saturated fat is necessarily bad. I don't have links but I've read a couple of good studies that showed saturated fat raised LDL in a cohort of sedentary participants, but had no impact on LDL in a cohort of regular exercisers. This suggests it may be more important to focus on exercise if you're worried about HDL/LDL.

semi-extrinsic 9y ago
Keep in mind there's also increasing evidence that HDL/LDL are symptoms, not causes of heart disease. Maybe the strongest is the failure of drugs that lower LDL and increase HDL - they don't make people better. E.g. Eli Lilly's Evacetrapib: tested on 20k patients over 24 months, LDL down 30%, HDL up 125% - but zero difference in cardiovascular health outcomes. Needless to say it failed the trial and has been scrapped. http://blogs.sciencemag.org/pipeline/archives/2017/05/18/now-this-is-a-drug-that-does-not-work http://blogs.sciencemag.org/pipeline/archives/2017/05/18/now...