4 ms·
Unfortunately I don't have the time to look into this specific approach, and I've been away from nanoparticle biology for about 5 years now, but... In almost a
by jballanc 9y ago
Unfortunately I don't have the time to look into this specific approach, and I've been away from nanoparticle biology for about 5 years now, but...
In almost all cases where nanoparticles have shown promise to treat various conditions, there remains one huge hurdle: how do you get them into the patient? i.e. Swallow a pill full of nanoparticles, and later that day you'll end up taking a nanoparticle-filled dump. Oral bioavailability is almost nonexistent. The only practical delivery mechanism is IV. For treating cancer, that's fine. Most advanced chemotherapy drugs already are delivered via IV. For an antibiotic, which will see greatest demand in locations with poor health facilities, i.e. with no real means of safely delivering IV drugs to large numbers of people, that's pretty much a deal breaker.