You've defined above why we use model organisms, but the original question wasn't questioning model organisms in general. I think we should work towards the or

You've defined above why we use model organisms, but the original question wasn't questioning model organisms in general. I think we should work towards the original posters challenge to validate our models are efficacious, not just normal and cheap. After spending a semester seminar reading rodent dietary studies, I am equally sceptical that mice are a good general model for diet.