35 ms·
A random theory, if you will: glucocorticoids have a weak affinity for the mineralocorticoid receptors (aldosterone, salt and water retention). The increased sa
by epmaybe 9y ago
A random theory, if you will: glucocorticoids have a weak affinity for the mineralocorticoid receptors (aldosterone, salt and water retention). The increased salt reabsorption caused by this could cause an osmotic gradient driving calcium excretion.
It sounds a bit too complicated though, where a transporter would fit in nicely.
- jrapdx3 9y agoI don't have any direct info re: mineralocorticoid effect on renal reabsorbtion of calcium, however the interaction of sodium and calcium has been studied as it is important in kidney disease, for example kidney stones, and osteoporosis as well. Here is an article on an excellent site that discusses some of the significant aspects of sodium/calcium regulation: http://kidneystones.uchicago.edu/does-too-much-protein-increase-stones-or-damage-bones/ http://kidneystones.uchicago.edu/does-too-much-protein-incre....