First off, the goal of starting a successful startup is not a goal that I would recommend to anyone. Startups are hard. They require painstaking work, large amo

First off, the goal of starting a successful startup is not a goal that I would recommend to anyone. Startups are hard. They require painstaking work, large amounts of risk, mental and emotional fortitude. Not to mention that the idea of focusing on creating a startup seems back asswards to begin with. You don't focus on creating a startup. You feel a need or see a problem and you focus on fixing it. If you feel like you have a solution that works then you consider going the startup route so you can fix your problem on a larger scale (startup is not the only option though). My point is that the motivation shouldn't be a startup for startup's sake. It should be a problem you want to solve and a problem that you think you're the one who's going to solve it best. If you go about it like that, then there's no need to "develop domain expertise" because you likely already have that (but you can dive deeper depending on the exact scenario).