3 ms·
I would highly recommend reading 'A brief history of everyone who ever lived' by Adam Rutherford. IIRC it contains a whole chapter on GWASs (pronounced jee-wazz
by ganonm 9y ago
I would highly recommend reading 'A brief history of everyone who ever lived' by Adam Rutherford. IIRC it contains a whole chapter on GWASs (pronounced jee-wazzes).
There are some phenotypes (characteristics) which clearly can be associated with a small number of genes (e.g. autosomal recessive disorders) , however for many phenotypes such as intelligence, it takes a lot more effort to correlate them with underlying genotypes. The fact that intelligence is approximately normally distributed is an indicator that there are many individual effects at play.
- bwestergard 9y agoganonm said "The fact that intelligence is approximately normally distributed is an indicator that there are many individual effects at play." Intelligence test scores are normally distributed by construction: the weighting of questions is adjusted to ensure normality on a sample population. That test scores are normally distributed in samples other than the normative one tells us nothing other than that the test designers succeeded. Contrast this with height, the measure of which is not defined in terms of a population distribution.