There are a few ways to make opioids less addicting. The most common strategy is to slow down absorption rate, which reduces the conditioning associated with dr

There are a few ways to make opioids less addicting. The most common strategy is to slow down absorption rate, which reduces the conditioning associated with drug-taking behavior. This can be done mechanically (sustained release pills or polymers) or chemically ("tie" the active molecule with a deactivating group which the body hydrolyses) http://www.sciencedirect.com/science/article/pii/S1369702116000304 http://www.sciencedirect.com/science/article/pii/S1369702116...