https://www.bio.org/sites/default/files/Clinical%20Development%20Success%20Rates%202006-2015%20-%20BIO,%20Biomedtracker,%20Amplion%202016.pdf https://www.bio.or

https://www.bio.org/sites/default/files/Clinical%20Development%20Success%20Rates%202006-2015%20-%20BIO,%20Biomedtracker,%20Amplion%202016.pdf https://www.bio.org/sites/default/files/Clinical%20Developme... > A more interesting question would be how many would have a significant safety issue without FDA approval. tl;dr > FDA approval (LOA) reveals that only 9.6% (n=9,985) of drug development programs successfully make it to market The FDA strikes a good balance I think. Its never going to be 100% successful but it does screen out many dangerous drugs.