I've seen it done (on a large-ish codebase), using Perl as a preprocessor for C. It looked good on paper and we were really enthusiastic when we came up with th

I've seen it done (on a large-ish codebase), using Perl as a preprocessor for C. It looked good on paper and we were really enthusiastic when we came up with the idea, but it quickly degenerated into the proverbial ad-hoc, informally-specified, bug-ridden, slow implementation of half of Common Lisp. In retrospect, we could have done worse, like use C++ :-).