3 ms·
Well this could end up being a sort of devil's bargain. Lower weight, better athletic performance, but increased DNA damage leading to other problems (I'd gues
by com2kid 10y ago
Well this could end up being a sort of devil's bargain.
Lower weight, better athletic performance, but increased DNA damage leading to other problems (I'd guess cancer being high up on that list).
- beefman 10y ago"...treatment with DNA-PK inhibitor protects against aging-associated decline in metabolism and physical fitness without increasing DSBs [double-strand breaks]... The most likely explanation for this paradox is that the ... DNA-PK inhibitor, like most inhibitor drugs, is a partial inhibitor at physiological doses. The residual DNA-PK activity may be sufficient to protect against the level of DNA DSBs generated naturally."