5 ms·

So Glaxo Smith Klein misrepresented adverse effects of paroxetine. This doesnt mean at all that the science behind SSRIs is "fraudulent". SSRIs are among the be

by zwwwdr 9y ago

So Glaxo Smith Klein misrepresented adverse effects of paroxetine. This doesnt mean at all that the science behind SSRIs is "fraudulent". SSRIs are among the best researched psychopharmaceuticals. And it is true that benzos make anxiety worse, long term, but that doesnt mean that they arent a valuable medication to treat anxiety.

tcj_phx 9y ago
Prozac was always defective too. The German FDA refused to approve it, way back when. https://news.ycombinator.com/item?id=14281643 https://news.ycombinator.com/item?id=14281643 The drug industry has a habit of coming out with a new "class" of drugs as soon as the patents for their old drugs expire. Or they patent a new combination for old over-the-counter chemicals. My father recently got prescribed something with a retail price of >$1000. He said he could buy the two OTC pills for about $15... this was something for his stomach + an nsaid, iirc.
- tptacek 9y ago
  The "German FDA" has certainly approved of fluoxetine (Prozac), which is simply sold under a different name there.
  - tcj_phx 9y ago
    maybe they eventually approved it, but they passed on it in 1984: – Three years before Prozac received approval by the US Food and Drug Administration in late 1987, the German BGA, that country’s FDA equivalent, had such serious reservations about Prozac’s safety that it refused to approve the antidepressant based on Lilly’s studies showing that previously nonsuicidal patients who took the drug had a fivefold higher rate of suicides and suicide attempts than those on older antidepressants, and a threefold higher rate than those taking placebos. [1] [1] http://www.baumhedlundlaw.com/media/boston_globe_prozac_revisted.htm http://www.baumhedlundlaw.com/media/boston_globe_prozac_revi... Two more links from this site ("note-to-self"): https://www.baumhedlundlaw.com/prozac-time-line/ https://www.baumhedlundlaw.com/prozac-time-line/ https://www.baumhedlundlaw.com/our-successes/advocacy-campaigns/ssri-documents/ https://www.baumhedlundlaw.com/our-successes/advocacy-campai...
    - tptacek 9y ago
      There's no "maybe" about it - Prozac is available in Germany, just under a different name.

by zwwwdr 9y ago

tcj_phx 9y ago

Prozac was always defective too. The German FDA refused to approve it, way back when. https://news.ycombinator.com/item?id=14281643 https://news.ycombinator.com/item?id=14281643 The drug industry has a habit of coming out with a new "class" of drugs as soon as the patents for their old drugs expire. Or they patent a new combination for old over-the-counter chemicals. My father recently got prescribed something with a retail price of >$1000. He said he could buy the two OTC pills for about $15... this was something for his stomach + an nsaid, iirc.

tptacek 9y ago
The "German FDA" has certainly approved of fluoxetine (Prozac), which is simply sold under a different name there.
- tcj_phx 9y ago
  maybe they eventually approved it, but they passed on it in 1984: – Three years before Prozac received approval by the US Food and Drug Administration in late 1987, the German BGA, that country’s FDA equivalent, had such serious reservations about Prozac’s safety that it refused to approve the antidepressant based on Lilly’s studies showing that previously nonsuicidal patients who took the drug had a fivefold higher rate of suicides and suicide attempts than those on older antidepressants, and a threefold higher rate than those taking placebos. [1] [1] http://www.baumhedlundlaw.com/media/boston_globe_prozac_revisted.htm http://www.baumhedlundlaw.com/media/boston_globe_prozac_revi... Two more links from this site ("note-to-self"): https://www.baumhedlundlaw.com/prozac-time-line/ https://www.baumhedlundlaw.com/prozac-time-line/ https://www.baumhedlundlaw.com/our-successes/advocacy-campaigns/ssri-documents/ https://www.baumhedlundlaw.com/our-successes/advocacy-campai...
  - tptacek 9y ago
    There's no "maybe" about it - Prozac is available in Germany, just under a different name.