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I always find it funny how people overblow the side effects from amphetamines and other performance enhancing drugs. Somehow these are "bad" because they are il

I always find it funny how people overblow the side effects from amphetamines and other performance enhancing drugs. Somehow these are "bad" because they are illegal. Just like how marajuana was "bad" but now its suddenly "okay" because it's legal. I have ADD - and an adderall prescription helped me get through alot of the bullshit for my bachelors degree. I can concentrate on things that interest me, but universities make you take a ton of unrelated courses and I just lost interest almost instantly on work. So for one year (my senior year) I had a prescription ranging from 15-30mg XR (30 was too high so I dropped down). In retrospect, I was able to quit cold turkey with minimal sides after graduating - got my heart scanned out of curiosity and its fine, cholesterol is fine, etc. etc. I think most drugs are safe if: 1. Used in the right doses for the right duration . 2. Only used on otherwise healthy individuals (this is an important one in the world of "everyone is equal") - I would not take adderall if I was obese since it is a stimulant and does increase BP / HR.

manyxcxi 9y ago
I take Vyvanse, so not directly the same. In fact I'm not sure if it and Adderal have the exact same effects on BP since they work differently. I'm definitely considered obese at 6'4" and 280lbs, but there's been literally no movement of my BP up or down since I've been on it. To agree with your point though: 1. Every physical I've ever had has had my vitals in good ranges (minus the weight) 2. I get strenuous physical excercise at least 4x/wk so I'm a spry tub of love I was worried about any possible issues with BP/HR during lifting sessions if I took it before workouts in the morning so I avoided it for a while until my doc reassured it should be fine. As with anything if I felt off, just back down the activity and don't do it tomorrow. I'd say if anything it allows me to run longer on the treadmill or elliptical because I don't get so god damn bored and ready to do something else.
- Bjartr 9y ago
  The difference in the brain for Adderall v. Vyvanse comes down to the concentration of which enantiomoers are (how much of which mirror image of amphetamine there is). It's all amphetamine, it all affects the same receptors. The real difference comes down to how long it stays available. Vyvanse sticks around in the blood longer than "plain" amphetamine, but amphetamine crosses into the brain much faster. Both of those are because the liver has to first cleave off the extra molecule tacked onto the amphetamine that makes it Vyvanse. That can only happen so fast, and until it does it's too big to cross the blood/brain barrier or get otherwise disposed of.
mattmanser 9y ago
Say a drug has a 1% chance to have an adverse affect. There's 99 out of 100 people like you saying "it's ok!". But there's the thousands of people who are left screwed up. What you think is completely irrelevant. It's a numbers game, not a personal anecdote game. How would this comment read if you'd got your heart scanned and it wasn't ok?
- drawnwren 9y ago
  You're right. However, the article's list of adverse affects are pretty laughable. You also just pulled numbers out of thin air. There are lots of anecdotes in this thread, and doctors seem pretty ok prescribing an FDA approved medication - so, aside from "it's being overprescribed" what is the downside?
- Zigurd 9y ago
  Either these drugs are somehow getting approved without monitoring provisions required, or 1% is much higher than the rate of negative side effects in reality.

manyxcxi 9y ago

I take Vyvanse, so not directly the same. In fact I'm not sure if it and Adderal have the exact same effects on BP since they work differently. I'm definitely considered obese at 6'4" and 280lbs, but there's been literally no movement of my BP up or down since I've been on it. To agree with your point though: 1. Every physical I've ever had has had my vitals in good ranges (minus the weight) 2. I get strenuous physical excercise at least 4x/wk so I'm a spry tub of love I was worried about any possible issues with BP/HR during lifting sessions if I took it before workouts in the morning so I avoided it for a while until my doc reassured it should be fine. As with anything if I felt off, just back down the activity and don't do it tomorrow. I'd say if anything it allows me to run longer on the treadmill or elliptical because I don't get so god damn bored and ready to do something else.

Bjartr 9y ago
The difference in the brain for Adderall v. Vyvanse comes down to the concentration of which enantiomoers are (how much of which mirror image of amphetamine there is). It's all amphetamine, it all affects the same receptors. The real difference comes down to how long it stays available. Vyvanse sticks around in the blood longer than "plain" amphetamine, but amphetamine crosses into the brain much faster. Both of those are because the liver has to first cleave off the extra molecule tacked onto the amphetamine that makes it Vyvanse. That can only happen so fast, and until it does it's too big to cross the blood/brain barrier or get otherwise disposed of.

mattmanser 9y ago

Say a drug has a 1% chance to have an adverse affect. There's 99 out of 100 people like you saying "it's ok!". But there's the thousands of people who are left screwed up. What you think is completely irrelevant. It's a numbers game, not a personal anecdote game. How would this comment read if you'd got your heart scanned and it wasn't ok?

drawnwren 9y ago
You're right. However, the article's list of adverse affects are pretty laughable. You also just pulled numbers out of thin air. There are lots of anecdotes in this thread, and doctors seem pretty ok prescribing an FDA approved medication - so, aside from "it's being overprescribed" what is the downside?
Zigurd 9y ago
Either these drugs are somehow getting approved without monitoring provisions required, or 1% is much higher than the rate of negative side effects in reality.