3 ms·
The promise of the "electroceutical" approach is localized neurotransmitter release: you want to enact increased ACh in the body (and localized within the body,
by joeyo 9y ago
The promise of the "electroceutical" approach is localized neurotransmitter release: you want to enact increased ACh in the body (and localized within the body, if possible) but not in the CNS, where it would likely result in undesired side effects.
You see the same phenomena in reverse with drugs intended for the brain (e.g. for treating depression). The severe side effects of those drugs are because the same neurotransmitter receptors involved in mood in the brain are involved in digestion in the gut.
- nikolay 9y agoIsn't A-GPC [0] proven to act just in the brain? [0]: https://examine.com/supplements/alpha-gpc/ https://examine.com/supplements/alpha-gpc/
- joeyo 9y agoIt looks like it is believed to be effective at crossing the blood-brain-barrier. Is that equivalent to acting just in the brain? No idea, but it seems unlikely.