I was curious about the NSAID number. Doing some quick research I came across this quote: "Mortality reported with NSAID use is generally linked to NSAID-assoc

I was curious about the NSAID number. Doing some quick research I came across this quote: "Mortality reported with NSAID use is generally linked to NSAID-associated GI bleeding, and the reported incidence is quite variable. Much of the literature reports 16,500 deaths annually as a result of NSAID-induced GI bleeding. However, it is important to put this number into perspective. This estimate was published in a 1999 observational study evaluating data from the Arthritis, Rheumatism, and Aging Medical Information System (ARAMIS).5 The database captured 19 NSAID-related GI bleeding deaths; the authors then extrapolated this number to the overall US population with arthritis. The 16,500 deaths has been considered overestimated or inaccurate because it was based on a small number of actual deaths and extrapolated inappropriately.6,7 A much smaller number was reported by Tarone and colleagues.7 They reported 3,200 deaths annually as a result of NSAID-induced GI bleeding based on US mortality data reported in the 1990s." Unfortunately I can't access the sources right now. https://www.practicalpainmanagement.com/treatments/pharmacological/opioids/ask-expert-do-nsaids-cause-more-deaths-opioids https://www.practicalpainmanagement.com/treatments/pharmacol...