It's not exactly the same problem. A cell model will hopefully not have to know the exact geometric configuration of a protein, as long as it contains a rich e

It's not exactly the same problem. A cell model will hopefully not have to know the exact geometric configuration of a protein, as long as it contains a rich enough collection of possible reactions with other proteins. Determining those reactions is difficult indeed, but it only has to be done once, and one can hope it will be done soon with quantum computers.