I just saw that Python's Makefile has support for PGO builds: https://github.com/python/cpython/blob/master/Makefile.pre.in#L479 https://github.com/python/cpyt

I just saw that Python's Makefile has support for PGO builds: https://github.com/python/cpython/blob/master/Makefile.pre.in#L479 https://github.com/python/cpython/blob/master/Makefile.pre.i... Not sure when it was added, but Python 2.7 has it. It's not clear to me how to tell if say my Ubuntu binary is built with PGO, but it's something I'm looking into.