3 ms·
I worked in a lab where we had a similar problem reconstructing 3d images from manual sections via the same procedure. Not only is it a painstaking process, bu
by hsdistefa 9y ago
I worked in a lab where we had a similar problem reconstructing 3d images from manual sections via the same procedure.
Not only is it a painstaking process, but some slices are lost due to human error while sectioning and the tissue is mechanically distorted when placed onto the slides (squished between the glass and the cover slip).
The solution was simple, albeit much more expensive than sectioning: just MRI scan the organ.
- foxyv 9y agoIf the sample is small enough you can always use an optical coherence microscope. You can get optical microscope resolutions in 3D of in-vivo samples. It's similar to a confocal microscope but with much higher resolution. Only thing is they can be dang expensive but nowhere near as much as an MRI. You can also get OCT devices for pretty cheap. They use them in optometrist offices for imaging retinas.
- namlem 9y agoDoes that really work? Can MRI achieve high enough resolutions? I thought it couldn't image anything smaller than 0.1mm or so.