Some interesting problems require more than 8-10 people, no matter how insanely great they are. I work at a highly interdisciplinary biotech startup. My instr

Some interesting problems require more than 8-10 people, no matter how insanely great they are. I work at a highly interdisciplinary biotech startup. My instrument SW team is eight guys, the tools-for-scientists team four, mathematicians are about five, etc.; then you have a bunch of physicists, chemists, biochemists, etc. etc. I'd rather suffer the problems of a large company than work on a more pure software problem.