I've done it 30 days in a row once. Tolerance is really quite negligible at these doses. However you do definitely notice full +50ug trips between for about 1-2

I've done it 30 days in a row once. Tolerance is really quite negligible at these doses. However you do definitely notice full +50ug trips between for about 1-2 days afterwards. Also, tolerance is maybe the wrong word as it suggests that all effects are diminished. With psychedelics, pretty much all of them except DMT when microdosing, it seems more like this for continous microdosing without days off: Day 3-4: Loss of the psychedelic "touch" in thought and perception, including associated creativity and easier ability to psychedelic thinking, now feels more like a stimulant without associated amphetamine bodyload Day 5-6: Slight loss of clarity Day 8-9: Further loss of clarity and beginning loss of energy and stimulation Day 12-13: Sober state becomes indistinguishable from microdose - true tolerance sets in