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No. It is because the next-gen sequencers just don't do what the old sequencers (sanger) do (sequence small regions of DNA at high accuracy). The new machines c
by danieltillett 10y ago
No. It is because the next-gen sequencers just don't do what the old sequencers (sanger) do (sequence small regions of DNA at high accuracy). The new machines can sequence a whole genome, but if you only want to look at small part of a genome then there is no replacement for Sanger sequencing.
Another surprising reason is the OEM manufacturer of the instrument (hitachi) basically over engineered the machines and built a tank. The machines just keep running and running.