What level of cache? For memory mapped regions there is madvise() DONT_NEED to tell the kernel to that you won't need this data again so don't bother with the

What level of cache? For memory mapped regions there is madvise() DONT_NEED to tell the kernel to that you won't need this data again so don't bother with the disk cache. For the CPU cache the non-temporal instructions MOVNTI that tells the CPU to not bother caching the move to prevent cache pollution.