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Nice work. Getting all of these tools in one place, in an easy to use way is not always easy. I'm well aware of what goes on behind the scenes to make something

by jfarlow 10y ago

Nice work. Getting all of these tools in one place, in an easy to use way is not always easy. I'm well aware of what goes on behind the scenes to make something like your alignment there as straightforward to use. The tricky part is what next :) I'm curious what your plans are - interoperability, private infrastructure, plugins/extensibility for others or just simply nice tools for people to use. I'd also be curious how you intend to approach the differences and distinctions between protein and DNA sequences. It doesn't look like you currently have much to do with an amino acid sequence. At Serotiny we've chosen to focus on the amino acid sequences for manipulation and leave the DNA in the background. It feels like it's often a trade-off - either/or. It's a challenge to get both into the same working environment without overwhelming the user. I'd be curious your thoughts on what we've built: https://serotiny.bio https://serotiny.bio btw - it's nice to see some ShowHNs show up for biological software.

folli 10y ago
Thanks for the encouraging words! I don't have any future plans yet, depends on the feedback I get and if there's enough interest for further features. I think you're touching a valid point, but it goes even further. There are many different use cases for a bio-software; a bench-worker has different requirements than a geneticist, microbiologists vs cell biologists etc, WGS and RNA-seq need an even more different toolset. It's impossible for a single software to cover all possible aspects of biology. The only thing you can do is focus on one group of users and try to fullfill their requirements.
- jfarlow 10y ago
  yep :) Unfortunately, the dearth of tools means everyone (coming from as many directions) feels like they must rebuild every tool - so there is a bit of a convergence right now - which spreads every tool thin. But the market for 'RNA-seq tools' is but a fraction of 'biochemical scientists', which itself is still a 'tiny' market to produce high-tech software for.

by jfarlow 10y ago

folli 10y ago

Thanks for the encouraging words! I don't have any future plans yet, depends on the feedback I get and if there's enough interest for further features. I think you're touching a valid point, but it goes even further. There are many different use cases for a bio-software; a bench-worker has different requirements than a geneticist, microbiologists vs cell biologists etc, WGS and RNA-seq need an even more different toolset. It's impossible for a single software to cover all possible aspects of biology. The only thing you can do is focus on one group of users and try to fullfill their requirements.

jfarlow 10y ago
yep :) Unfortunately, the dearth of tools means everyone (coming from as many directions) feels like they must rebuild every tool - so there is a bit of a convergence right now - which spreads every tool thin. But the market for 'RNA-seq tools' is but a fraction of 'biochemical scientists', which itself is still a 'tiny' market to produce high-tech software for.