4 ms·

Have you already done a 23andMe analysis? If so, you can check out https://promethease.com/ https://promethease.com/. It's exactly what you're looking for as th

by sushid 10y ago

Have you already done a 23andMe analysis? If so, you can check out https://promethease.com/ https://promethease.com/. It's exactly what you're looking for as they have constant updates that make it worth your while to rescan every year or so.

kstrauser 10y ago
Promethease is awesome. I uploaded my 23andMe data to it and got back the kind of data I'd been hoping for in the first place. Fair warning: the UI is very geeky. I think any HN reader should be able to find their way around without trouble, but I wouldn't recommend it to my non-technical friends or family.
fudged71 10y ago
Why would you need to be rescanned? Does your DNA change that often?
- adenadel 10y ago
  They mean rescan with the Promethease software. Our knowledge around genetic variation is evolving rapidly.
- sushid 10y ago
  Not your DNA, but your Promethease analysis can be redone every year or so as they're constantly adding new analyses.
  - fudged71 10y ago
    Makes sense, thanks!
echelon 10y ago
Thanks! This is way more interesting than the data 23andMe provides.
nojvek 10y ago
Are you saying 23&Me gives you a file with the full list of chromosome's ACGT data? I've always wanted that. Also is prometheus and open source analyzer?
- berberous 10y ago
  23&Me will let you download a text file with the ACGT data, but only for the SNPs that it has. 23&Me does not sequence your full genome, so the SNPs available are a small subset of your DNA. Prometheus is not open-source (I think), but all it does is read various files with DNA data (like the 23&me export), and match it up with the information in SNPedia (a Wikipedia-like open repository of what we know about certain SNPs), and then exports it to a pretty HTML/JS web report for you that you can download and save.
  - lawnchair_larry 10y ago
    Is it possible to do client side? I'd rather download the db and match it locally than ship my genome to them.
    - berberous 10y ago
      Yes. The author pushes people to the web version since it's more up to date, easier to maintain, etc., but there's a local version, see: http://snpedia.com/index.php/Promethease/Desktop http://snpedia.com/index.php/Promethease/Desktop http://snpedia.com/index.php/Promethease/privacy http://snpedia.com/index.php/Promethease/privacy
jtmcmc 10y ago
IIRC but this is what 23andMe used to do before their FDA smackdown.

by sushid 10y ago

kstrauser 10y ago

Promethease is awesome. I uploaded my 23andMe data to it and got back the kind of data I'd been hoping for in the first place. Fair warning: the UI is very geeky. I think any HN reader should be able to find their way around without trouble, but I wouldn't recommend it to my non-technical friends or family.

fudged71 10y ago

Why would you need to be rescanned? Does your DNA change that often?

adenadel 10y ago
They mean rescan with the Promethease software. Our knowledge around genetic variation is evolving rapidly.
sushid 10y ago
Not your DNA, but your Promethease analysis can be redone every year or so as they're constantly adding new analyses.
- fudged71 10y ago
  Makes sense, thanks!

echelon 10y ago

Thanks! This is way more interesting than the data 23andMe provides.

nojvek 10y ago

Are you saying 23&Me gives you a file with the full list of chromosome's ACGT data? I've always wanted that. Also is prometheus and open source analyzer?

berberous 10y ago
23&Me will let you download a text file with the ACGT data, but only for the SNPs that it has. 23&Me does not sequence your full genome, so the SNPs available are a small subset of your DNA. Prometheus is not open-source (I think), but all it does is read various files with DNA data (like the 23&me export), and match it up with the information in SNPedia (a Wikipedia-like open repository of what we know about certain SNPs), and then exports it to a pretty HTML/JS web report for you that you can download and save.
- lawnchair_larry 10y ago
  Is it possible to do client side? I'd rather download the db and match it locally than ship my genome to them.
  - berberous 10y ago
    Yes. The author pushes people to the web version since it's more up to date, easier to maintain, etc., but there's a local version, see: http://snpedia.com/index.php/Promethease/Desktop http://snpedia.com/index.php/Promethease/Desktop http://snpedia.com/index.php/Promethease/privacy http://snpedia.com/index.php/Promethease/privacy

jtmcmc 10y ago

IIRC but this is what 23andMe used to do before their FDA smackdown.