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Here's something I don't understand about this, maybe someone can help explain it. To implement a change in a person, you would have to modify the DNA in every
by aerovistae 10y ago
Here's something I don't understand about this, maybe someone can help explain it. To implement a change in a person, you would have to modify the DNA in every cell in their body, would you not? I understand how the change is made to DNA with CRISPR, that's clear, but how can that change be propagated to affect an entire individual? Even an embryo is multicellular, is it not?
- gort 10y ago> Even an embryo is multicellular, is it not? I've not read the article yet, but an answer to this question is, "not at the very start".
- sxv 10y agoIf you were to modify the genome of a sperm cell and fertilize an egg cell with it, then the resulting individual will have the modifications in all of its cells.
- dnautics 10y agothe answer is you can't and there aren't any reasonable proposals to do so at the moment (this is not to say there won't be in the future). Modifying embryos at the 1-cell stage, however, is doable.