4 ms·
Have you looked into what combination of mutation rates and number of required mutations would be necessary for your model to work? Usually people say it is som
by nonbel 10y ago
Have you looked into what combination of mutation rates and number of required mutations would be necessary for your model to work? Usually people say it is something like 10^-8 per bp per division and you need to collect 3-6 mutations to get cancer.
- sandworm101 10y agoIsn't cancer predicated on mutations that result in uncontrolled cell growth? I imagine there are a great many mutations that result in cell death or an inability to properly divide. Those mutations wouldn't contribute to cancer risk. So maybe you need 3-6 but only amongst those bits of DNA that actually matter.
- nonbel 10y agoYes, that is correct. It would only be some "special" combinations of mutations, not just any set.