2 ms·
I didn't see any data on improved survival/toxicity in those papers. The closest was Fig S4B/C of the last one (Rauch et al 2017), which shows some of the inhib
by nonbel 10y ago
I didn't see any data on improved survival/toxicity in those papers. The closest was Fig S4B/C of the last one (Rauch et al 2017), which shows some of the inhibitors are toxic too. So evidence for that may exist somewhere, but not there.
Also, I think if they were serious about addressing this toxicity issue they would be include simple charts of the number of cells over time and number of "modified" cells over time. Then they (and the reader) can easily compare the toxicity and efficacy of different techniques.