It depends on what you are doing. I find programming on one monitor to be fine, but I have a schedule with email, excel workbooks to compare with Visio diagram

It depends on what you are doing. I find programming on one monitor to be fine, but I have a schedule with email, excel workbooks to compare with Visio diagrams / Word docs, Web conferences, a soft phone, and my Surface happens to be touch/tablet with OneNote. Virtual desktops with multiple monitors works great on Windows 10, but other than when I am running a VM, I never use them. However, one major gripe I have with Windows 10 is how stupid it is with multiple monitors. If I click on a link, open a file, or open an app with the Start Menu, I expect it to open in the same window. Not Windows 10, I swear it has an algorithm developed just to pick the least expected monitor. It is practically a game of whack-a-mole. This alone is a huge unnecessary UX productivity loss that doesn't exist with a single display.