For high performance, assembly language is frequently the best choice, at least for the central algorithmic core. Performance frequently demands access to the r

For high performance, assembly language is frequently the best choice, at least for the central algorithmic core. Performance frequently demands access to the raw machine and a careful balance between the hardware and the algorithm not available in a modular, flexible, easy-to-understand compiled programming language. See, for example, the techniques used for the Intel CPUs in Lee, Victor W., et al. "Debunking the 100X GPU vs. CPU myth: an evaluation of throughput computing on CPU and GPU." ACM SIGARCH Computer Architecture News 38.3 (2010): 451-460.