You've already gotten some good answers while I was finishing my coffee, but here goes anyway. The only time I miss a mouse is when I want to fire up a game th

You've already gotten some good answers while I was finishing my coffee, but here goes anyway. The only time I miss a mouse is when I want to fire up a game that actually runs on my Mac (Dwarf Fortress, Rimworld, etc.). I'd say the main reason I don't miss a mouse in vim is because I don't use a mouse anywhere else on my Mac. On a fresh format I create 4 desktops, and I bind CMD+1-4 to switch between these. Whenever I want to launch chrome/term/mail/whatever I use CMD+space and launch it directly from Spotlight. I use Magnet (http://magnet.crowdcafe.com http://magnet.crowdcafe.com - no affiliation, just a fan) to maximize/minimize/layout windows without having to use the _remarkably awful_ Mac window management UI. While within vim I don't miss a scroll-wheel because bouncing around with / and ? is just so, so, so much faster. I really cannot stress enough how slow it now feels to scroll up and down a file searching for a specific string when I'm forced to do so. It's maddening for me now. Your question re: a project panel, etc, is probably the best one. I think I may be an outlier here. I don't use NERDtree, but a lot (most, in fact) of my friends who use vim do. There are really two use cases for opening a file - direct from the term or in concert with an already open file. I typically know the structure of a project so I can just cd around or vim right/to/the/file.js If I'm already editing something I'll usually just :vsp to/the/other/file.erb or if I'm really lost as to where I am or where I'm trying to go I'll just CTRL+Z back to the term, cd & ag around until I find myself, fg back to vim, then :vsp to/where/I/now/know/Im/going.scss I suspect if I actually spent the time to learn NERDtree I may be able to get around unknown projects better, but I've always felt pretty good about my workflow so I've just never committed to it.