Wow crazy. The article ends by speculating that activities that activate “heat shock protein” pathway may help blood sugar control. It’s interesting b/c this p

Wow crazy. The article ends by speculating that activities that activate “heat shock protein” pathway may help blood sugar control. It’s interesting b/c this pathway is well-studied in microbes like e coli and we were taught about it in my genomics classes. But I didn’t realize it was conserved to the point that it is significant in humans (maybe it isn’t). It’s a bit of a misnomer, actually. It was identified in e. coli as molecularly central to their response when exposed to immediate stress, such as going from 32 C to 40 C, but also on exposure to UV, or cold?, pH change, salinity change etc Basically it’s bacterial-molecular version of calling 911. But because it was first identified by heat shock experimental condition, that’s what it was named. Did the author just read about "heat shock protein" in humans and assume it was related how gene expression changes in human cells when body temperature is elevated 1 degree C? Or was it mentioned in the primary literature they are summarizing...