5 ms·

You sure it was Type 1? Generally people are diagnosed with Type 1 at a very young age, since it is caused by your own immune system destroying beta cells in t

You sure it was Type 1? Generally people are diagnosed with Type 1 at a very young age, since it is caused by your own immune system destroying beta cells in the pancreas, which if untreated results in eventual death. Type 2 is more often associated with age and diet. It is the most common type in particular at later ages, but some people get it younger due to genetic predisposition.

epmaybe 10y ago
Type 1.5 is adult onset autoimmune diabetes
- zaroth 10y ago
  That's a bit of an oversimplification. T1 is auto-immune -- the body loses the ability to produce insulin, and you can detect autoantibodies in the blood. T2 is insulin resistance, and generally has no autoimmune component and no autoantibodies present. Typically T1D comes on all at once; the autoantibodies destroy the insulin producing beta cells and the patient needs exogenous insulin starting immediately. A subset of adult onset T1D displays a much slower progression of the destruction of beta cells. This is called LADA (latent autoimmune diabetes of adults”) or slow-progressing T1D and more recently T1.5D. Similarly, some T2D patients also show evidence of autoantibodies however their beta cells are still largely functioning. So now we further split into groups; Type 1–LADA, Type 1.5 or “double” diabetes, and Type 2 diabetes with autoantibodies. This is a good overview: https://www.diabetesselfmanagement.com/diabetes-resources/definitions/type-1-5-diabetes/ https://www.diabetesselfmanagement.com/diabetes-resources/de...
  - epmaybe 10y ago
    Thanks! I'm a little rough on my diabetes pathology/immunology, this was a good review :)
zaroth 10y ago
This is really not the kind of thing that people with a diagnosis tend to be confused about. There is early and late-onset T1D. About 25% of T1D is diagnosed as an adult [1] [1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925303/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925303/
bluemax 10y ago
The folks at the hospital were not sure at first. I'm neither young, nor old and overweight so there were different opinions before some specific blood test was done.
parenthesis 10y ago
The UK Prime Minister, Theresa May, was diagnosed with type 1 diabetes in her mid 50s, just a few years ago.

epmaybe 10y ago

Type 1.5 is adult onset autoimmune diabetes

zaroth 10y ago
That's a bit of an oversimplification. T1 is auto-immune -- the body loses the ability to produce insulin, and you can detect autoantibodies in the blood. T2 is insulin resistance, and generally has no autoimmune component and no autoantibodies present. Typically T1D comes on all at once; the autoantibodies destroy the insulin producing beta cells and the patient needs exogenous insulin starting immediately. A subset of adult onset T1D displays a much slower progression of the destruction of beta cells. This is called LADA (latent autoimmune diabetes of adults”) or slow-progressing T1D and more recently T1.5D. Similarly, some T2D patients also show evidence of autoantibodies however their beta cells are still largely functioning. So now we further split into groups; Type 1–LADA, Type 1.5 or “double” diabetes, and Type 2 diabetes with autoantibodies. This is a good overview: https://www.diabetesselfmanagement.com/diabetes-resources/definitions/type-1-5-diabetes/ https://www.diabetesselfmanagement.com/diabetes-resources/de...
- epmaybe 10y ago
  Thanks! I'm a little rough on my diabetes pathology/immunology, this was a good review :)

zaroth 10y ago

This is really not the kind of thing that people with a diagnosis tend to be confused about. There is early and late-onset T1D. About 25% of T1D is diagnosed as an adult [1] [1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925303/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925303/

bluemax 10y ago

The folks at the hospital were not sure at first. I'm neither young, nor old and overweight so there were different opinions before some specific blood test was done.

parenthesis 10y ago

The UK Prime Minister, Theresa May, was diagnosed with type 1 diabetes in her mid 50s, just a few years ago.