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This kind of point mutation is exactly the kind of issue that CRISPR is capable of fixing. This can be done today. The issues are specificity and delivery of
by jfarlow 10y ago
This kind of point mutation is exactly the kind of issue that CRISPR is capable of fixing. This can be done today. The issues are specificity and delivery of the fix. Delivery is hard to do non-invasively without side effects, and the 'fix' must not only correct only the error, but also not 'correct' a non-error elsewhere. Getting the 'patch' to the right place, and making sure the patch only affects exactly this sequence is now the hard part - actually creating the patch is doable today.