Hi there! As the spec explains, this is a Markdown specific blacklist that prevent the tags that would otherwise "break" the content of the Markdown document.

Hi there! As the spec explains, this is a Markdown specific blacklist that prevent the tags that would otherwise "break" the content of the Markdown document. A document that contains these tags will not be parsed properly by an HTML5 compliant parser; the parser will "swallow" other chunks of Markdown content that come after the tags. Hence, we disable the tags altogether. This is an UX feature, not a security feature. XSS prevention, and a plethora of other security checks, are performed by our user content stack -- but this functionality is shared for all markup languages in GitHub (MD, RST, ASCIIDOC, ...), so it's not discussed in this spec.