The risk for liver damage related to Tylenol is mostly related to chronic alcohol use. Safer guidelines in the US have decreased the maximum from 4 g in 24 hour

The risk for liver damage related to Tylenol is mostly related to chronic alcohol use. Safer guidelines in the US have decreased the maximum from 4 g in 24 hours to 3 g. This is still 4 doses every 6 hours. NSAID use gets iffy in diabetics. Especially if you've had poor blood glucose control, your kidneys may have been damaged over time. This is a discussion to have with your primary care provider.