2 ms·
Well, it's not all one:one though [1]. If you're messing with transcription factor, who knows what the domino effects will be. Tiny changes might end up trigger
by itchyjunk 10y ago
Well, it's not all one:one though [1]. If you're messing with transcription factor, who knows what the domino effects will be. Tiny changes might end up triggering phenotypes [2] already present that wouldn't have been expressed without those edits.
The idea that there is only about 2% difference between a chimp and man highlights this point.[3]
[1] https://en.wikipedia.org/wiki/Transcription_factor https://en.wikipedia.org/wiki/Transcription_factor
[2] https://en.wikipedia.org/wiki/Phenotype https://en.wikipedia.org/wiki/Phenotype
[3] http://discovermagazine.com/2006/apr/chimp-genome http://discovermagazine.com/2006/apr/chimp-genome
Disclaimer : Not arguing for or against.
- sfeng 10y agoOf all the things to modify though, why a transcription factor? Of course there are things in the genome which modifications of would have problematic results. The question is if we should modify those parts we do think would lead to a better outcome, not the ones we know won't.